University of California San Francisco

The tail that wags the dog: p12, the smallest subunit of DNA polymerase δ, is degraded by ubiquitin ligases in response to DNA damage and during cell cycle progression. (24300032)

Lee MY, Zhang S, Lin SH, Wang X, Darzynkiewicz Z, Zhang Z, Lee EY PMID: 24300032

PDIP38 is translocated to the spliceosomes/nuclear speckles in response to UV-induced DNA damage and is required for UV-induced alternative splicing of MDM2. (23989611)

Wong A, Zhang S, Mordue D, Wu JM, Zhang Z, Darzynkiewicz Z, Lee EY, Lee MY PMID: 23989611

A novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phase. (23913683)

Zhang S, Zhao H, Darzynkiewicz Z, Zhou P, Zhang Z, Lee EY, Lee MY PMID: 23913683

Identification of RNF8 as a ubiquitin ligase involved in targeting the p12 subunit of DNA polymerase δ for degradation in response to DNA damage. (23233665)

Zhang S, Zhou Y, Sarkeshik A, Yates JR, Thomson TM, Zhang Z, Lee EY, Lee MY PMID: 23233665

Regulation of human DNA polymerase delta in the cellular responses to DNA damage. (23047826)

Lee MY, Zhang S, Lin SH, Chea J, Wang X, LeRoy C, Wong A, Zhang Z, Lee EY PMID: 23047826

Spatiotemporal recruitment of human DNA polymerase delta to sites of UV damage. (22801543)

Chea J, Zhang S, Zhao H, Zhang Z, Lee EY, Darzynkiewicz Z, Lee MY PMID: 22801543

Characterization of human DNA polymerase delta and its subassemblies reconstituted by expression in the MultiBac system. (22723953)

Zhou Y, Meng X, Zhang S, Lee EY, Lee MY PMID: 22723953

Structure of monoubiquitinated PCNA: implications for DNA polymerase switching and Okazaki fragment maturation. (22592530)

Zhang Z, Zhang S, Lin SH, Wang X, Wu L, Lee EY, Lee MY PMID: 22592530

P50, the small subunit of DNA polymerase delta, is required for mediation of the interaction of polymerase delta subassemblies with PCNA. (22073260)

Wang Y, Zhang Q, Chen H, Li X, Mai W, Chen K, Zhang S, Lee EY, Lee MY, Zhou Y PMID: 22073260

Production of recombinant human DNA polymerase delta in a Bombyx mori bioreactor. (21789240)

Zhou Y, Chen H, Li X, Wang Y, Chen K, Zhang S, Meng X, Lee EY, Lee MY PMID: 21789240