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Boris Bastian, MD, PhD
Boris Bastian, MD, PhD
Mutant Gq/11 promote uveal melanoma tumorigenesis by activating YAP.
Yu FX, Luo J, Mo JS, Liu G, Kim YC, Meng Z, Zhao L, Peyman G, Ouyang H, Jiang W, Zhao J, Chen X, Zhang L, Wang CY, Bastian BC, Zhang K, Guan KL PMID: 24882516
In melanoma, Hippo signaling is affected by copy number alterations and YAP1 overexpression impairs patient survival.
Menzel M, Meckbach D, Weide B, Toussaint NC, Schilbach K, Noor S, Eigentler T, Ikenberg K, Busch C, Quintanilla-Martinez L, Kohlhofer U, Göke A, Göke F, Handgretinger R, Ottmann C, Bastian BC, Garbe C, Röcken M, Perner S, Kohlbacher O, Bauer J PMID: 24703331
How does pain affect eating and food pleasure?
Leknes S, Bastian B PMID: 24418458
Chromosomal copy number analysis in melanoma diagnostics.
North JP, Vemula SS, Bastian BC PMID: 24258981
Kinase fusions are frequent in Spitz tumours and spitzoid melanomas.
Wiesner T, He J, Yelensky R, Esteve-Puig R, Botton T, Yeh I, Lipson D, Otto G, Brennan K, Murali R, Garrido M, Miller VA, Ross JS, Berger MF, Sparatta A, Palmedo G, Cerroni L, Busam KJ, Kutzner H, Cronin MT, Stephens PJ, Bastian BC PMID: 24445538
The molecular pathology of melanoma: an integrated taxonomy of melanocytic neoplasia.
Bastian BC PMID: 24460190
Sporadic naturally occurring melanoma in dogs as a preclinical model for human melanoma.
Simpson RM, Bastian BC, Michael HT, Webster JD, Prasad ML, Conway CM, Prieto VM, Gary JM, Goldschmidt MH, Esplin DG, Smedley RC, Piris A, Meuten DJ, Kiupel M, Lee CC, Ward JM, Dwyer JE, Davis BJ, Anver MR, Molinolo AA, Hoover SB, Rodriguez-Canales J, Hewitt SM PMID: 24128326
Combined PKC and MEK inhibition in uveal melanoma with GNAQ and GNA11 mutations.
Chen X, Wu Q, Tan L, Porter D, Jager MJ, Emery C, Bastian BC PMID: 24141786
Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy.
Botton T, Yeh I, Nelson T, Vemula SS, Sparatta A, Garrido MC, Allegra M, Rocchi S, Bahadoran P, McCalmont TH, LeBoit PE, Burton EA, Bollag G, Ballotti R, Bastian BC PMID: 23890088
Targeting activated KIT signaling for melanoma therapy.
Bastian BC, Esteve-Puig R PMID: 23940224
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