University of California San Francisco

Keratinocyte-TRPV1 sensory neuron interactions in a genetically controllable mouse model of chronic neuropathic itch.

Crowther AJ, Kashem SW, Jewell ME, Le Chang H, Midavaine É, Rosa Casillas M, Danchine V, Rodriguez S, Kania A, Chen R, Braz JM, Basbaum AI PMID: 40498457

Meningeal regulatory T cells inhibit nociception in female mice.

Midavaine É, Moraes BC, Benitez J, Rodriguez SR, Braz JM, Kochhar NP, Eckalbar WL, Tian L, Domingos AI, Pintar JE, Basbaum AI, Kashem SW PMID: 40179196

Regulatory T cell-derived enkephalin gates nociception.

Midavaine É, Moraes BC, Benitez J, Rodriguez SR, Braz JM, Kochhar NP, Eckalbar WL, Domingos AI, Pintar JE, Basbaum AI, Kashem SW PMID: 38798460

Discovery of a CCR2-targeting pepducin therapy for chronic pain.

Midavaine É, Brouillette RL, Théberge E, Mona CE, Kashem SW, Côté J, Zeugin V, Besserer-Offroy É, Longpré JM, Marsault É, Sarret P PMID: 38823470

Neuropeptide substance P alters stem cell fate to aid wound healing and promote epidermal stratification through asymmetric stem cell divisions.

Khalifa A, Xiao T, Abegaze B, Weisenberger T, Charruyer A, Sanad S, AbuElnasr T, Kashem SW, Fassett M, Ghadially R PMID: 38301639

Can Serum Biomarkers for Prurigo Nodularis Expose Pathophysiology or Just Treatment Response?

Kashem SW, Fassett MS PMID: 37556170

Tetracycline transactivator overexpression in keratinocytes triggers a TRPV1 primary sensory neuron-dependent neuropathic itch

Crowther AJ, Kashem SW, Jewell ME, Chang HL, Casillas MR, Midavaine E, Rodriguez S, Braz JM, Kania A, Basbaum AI PMID:

Spontaneous resolution of intractable prurigo nodularis after subinsular cortex stroke.

Kashem SW, Motzkin JC, Leslie KS PMID: 36687303

Local IL-23 is required for proliferation and retention of skin-resident memory TH17 cells.

Whitley SK, Li M, Kashem SW, Hirai T, Igyártó BZ, Knizner K, Ho J, Ferris LK, Weaver CT, Cua DJ, McGeachy MJ, Kaplan DH PMID: 36367947

A single-cell transcriptional gradient in human cutaneous memory T cells restricts Th17/Tc17 identity.

Cook CP, Taylor M, Liu Y, Schmidt R, Sedgewick A, Kim E, Hailer A, North JP, Harirchian P, Wang H, Kashem SW, Shou Y, McCalmont TC, Benz SC, Choi J, Purdom E, Marson A, Ramos SBV, Cheng JB, Cho RJ PMID: 35977472